Neuropilin 1 antibody (AA 22-131)

Catalog No. ABIN1327097

There are 2+ publications for this product available. The Mouse Monoclonal anti-Neuropilin 1 antibody is suitable to detect Neuropilin 1 in samples from Human. It has been validated for WB, IP and ELISA.

Quick Overview for Neuropilin 1 antibody (AA 22-131) (ABIN1327097)

Target: Neuropilin 1 (NRP1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neuropilin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA

Clone: 1B3

Product Details anti-Neuropilin 1 Antibody

Binding Specificity: AA 22-131

Purpose: Mouse monoclonal antibody raised against a partial recombinant NRP1.

Sequence: FRNDKCGDTI KIESPGYLTS PGYPHSYHPS EKCEWLIQAP DPYQRIMINF NPHFDLEDRD CKYDYVEVFD GENENGHFRG KFCGKIAPPP VVSSGPFLFI KFVSDYETHG

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: NRP1 (NP_003864, 22 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Neuropilin 1 antibody (ABIN1327097)

Ohkusu-Tsukada, Ohta, Kawakami, Toda: "Adjuvant effects of formalin-inactivated HSV through activation of dendritic cells and inactivation of myeloid-derived suppressor cells in cancer immunotherapy." in: International journal of cancer. Journal international du cancer, Vol. 128, Issue 1, pp. 119-31, (2010) (PubMed).

Klee, Finlay, McDonald, Attewell, Hebrink, Dyer, Love, Vasmatzis, Li, Beechem, Klee: "Bioinformatics methods for prioritizing serum biomarker candidates." in: Clinical chemistry, Vol. 52, Issue 11, pp. 2162-4, (2007) (PubMed).

Target Details for Neuropilin 1

Target: Neuropilin 1 (NRP1)

Alternative Name: NRP1

Background: Full Gene Name: neuropilin 1
Synonyms: BDCA4,CD304,DKFZp686A03134,DKFZp781F1414,NP1,NRP,VEGF165R

Gene ID: 8829

NCBI Accession: NM_003873

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals