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METTL3 antibody (AA 1-580)

The Mouse Polyclonal anti-METTL3 antibody has been validated for WB and IF. It is suitable to detect METTL3 in samples from Human. There is 1 publication available.
Catalog No. ABIN1327559

Quick Overview for METTL3 antibody (AA 1-580) (ABIN1327559)

Target

See all METTL3 Antibodies
METTL3 (Methyltransferase Like 3 (METTL3))

Reactivity

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Human

Host

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Mouse

Clonality

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Polyclonal

Conjugate

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This METTL3 antibody is un-conjugated

Application

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Western Blotting (WB), Immunofluorescence (IF)
  • Binding Specificity

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    AA 1-580

    Purpose

    Mouse polyclonal antibody raised against a full-length human METTL3 protein.

    Sequence

    MSDTWSSIQA HKKQLDSLRE RLQRRRKQDS GHLDLRNPEA ALSPTFRSDS PVPTAPTSGG PKPSTASAVP ELATDPELEK KLLHHLSDLA LTLPTDAVSI CLAISTPDAP ATQDGVESLL QKFAAQELIE VKRGLLQDDA HPTLVTYADH SKLSAMMGAV AEKKGPGEVA GTVTGQKRRA EQDSTTVAAF ASSLVSGLNS SASEPAKEPA KKSRKHAASD VDLEIESLLN QQSTKEQQSK KVSQEILELL NTTTAKEQSI VEKFRSRGRA QVQEFCDYGT KEECMKASDA DRPCRKLHFR RIINKHTDES LGDCSFLNTC FHMDTCKYVH YEIDACMDSE APGSKDHTPS QELALTQSVG GDSSADRLFP PQWICCDIRY LDVSILGKFA VVMADPPWDI HMELPYGTLT DDEMRRLNIP VLQDDGFLFL WVTGRAMELG RECLNLWGYE RVDEIIWVKT NQLQRIIRTG RTGHWLNHGK EHCLVGVKGN PQGFNQGLDC DVIVAEVRST SHKPDEIYGM IERLSPGTRK IELFGRPHNV QPNWITLGNQ LDGIHLLDPD VVARFKQRYP DGIISKPKNL

    Cross-Reactivity

    Human

    Characteristics

    Antibody reactive against mammalian transfected lysate.

    Immunogen

    METTL3 (NP_062826.2, 1 a.a. ~ 580 a.a) full-length human protein.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    In 1x PBS, pH 7.4

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Ping, Sun, Wang, Xiao, Yang, Wang, Adhikari, Shi, Lv, Chen, Zhao, Li, Yang, Dahal, Lou, Liu, Huang, Yuan, Zhu, Cheng, Zhao, Wang, Rendtlew Danielsen, Liu, Yang: "Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase." in: Cell research, Vol. 24, Issue 2, pp. 177-89, (2014) (PubMed).

  • Target

    METTL3 (Methyltransferase Like 3 (METTL3))

    Alternative Name

    METTL3

    Background

    Full Gene Name: methyltransferase like 3
    Synonyms: IME4,M6A,MGC4336,MT-A70,Spo8

    Gene ID

    56339

    NCBI Accession

    NM_019852
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