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CD8 alpha antibody

CD8A Reactivity: Pig FACS Host: Mouse Monoclonal 76-2-11 unconjugated
Catalog No. ABIN135476
  • Target See all CD8 alpha (CD8A) Antibodies
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Reactivity
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    • 46
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    Pig
    Host
    • 143
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    • 89
    Mouse
    Clonality
    • 254
    • 96
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    Monoclonal
    Conjugate
    • 122
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    This CD8 alpha antibody is un-conjugated
    Application
    • 281
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    Flow Cytometry (FACS)
    Specificity
    Porcine CD8α, Mr 35 kDa
    Characteristics
    Mouse Anti-Porcine CD8a-UNLB
    Purification
    Purified
    Immunogen
    Fresh dd miniature swine thymocytes
    Clone
    76-2-11
    Isotype
    IgG2a
    Top Product
    Discover our top product CD8A Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , IP - Reported in literature , Block - Reported in literature , Depletion - Reported in literature , CMCD - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT and AF488 conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Comment

    Cytotoxicity assays, In vivo depletion of CD8+ cells

    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Preservative
    Without preservative
    Handling Advice
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Alternative Name
    CD8a (CD8A Products)
    Background
    Porcine CD8, a type I transmembrane glycoprotein, is expressed as either a CD8 homodimer or a CD8 heterodimer. It is found on most thymocytes, and on the suppressor/cytotoxic subpopulation of peripheral T cells. CD8 functions primarily as a co-receptor with MHC Class I-restricted T-cell receptors in antigen recognition.
    Pathways
    TCR Signaling
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