TGF-beta antibody (AA 378-382)
Quick Overview for TGF-beta antibody (AA 378-382) (ABIN1355901)
Target
See all TGF-beta (TGFb) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 378-382
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Specificity
- The antibody detects endogenous level of total TGF-b protein.
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Immunogen
- Peptide sequence around AA 378-382 (Q-L-S-N-M) derived from Human TGF-b.
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Application Notes
- Western blotting: 1: 500-1: 1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Storage
- 4 °C/-20 °C
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- TGF-beta (TGFb)
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Alternative Name
- TGF-B
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Background
- Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
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Molecular Weight
- 45-65 kDa
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Pathways
- EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
Target
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