CD16 antibody (FITC)

Catalog No. ABIN135755

The Mouse Monoclonal anti-CD16 antibody has been validated for FACS. It is suitable to detect CD16 in samples from Human.

Quick Overview for CD16 antibody (FITC) (ABIN135755)

Target: CD16

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: GRM1

Product Details anti-CD16 Antibody (FITC)

Specificity: Human CD16, Mr 50-65 kDa

Characteristics: Mouse Anti-Human CD16-FITC

Immunogen: Mononuclear cells from a prolymphocytic B-leukemia

Isotype: IgG2a

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , WB - Reported in literature , ELISA - Reported in literature , CMCD - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, SPRD, AF488, AF647, and AF700 conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Restrictions: For Research Use only

Handling

Buffer: 100 tests in 1.0 mL of PBS/Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for CD16

Target: CD16

Alternative Name: CD16

Background: CD16, a member of the immunoglobulin superfamily, is a 50-65 kDa glycoprotein found as both a transmembrane and GPI-linked form. The transmembrane form of CD16 is expressed on NK cells, granulocytes, macrophages, and mast cells but not on eosinophils. The GPI-anchored type of CD16 is found only on neutrophils. CD16 is involved in NK activation and signal transduction.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process