VCAM1 antibody

Catalog No. ABIN1383722

The Mouse Monoclonal anti-VCAM1 antibody has been validated for Func. It is suitable to detect VCAM1 in samples from Human. There are 4+ publications available.

Quick Overview for VCAM1 antibody (ABIN1383722)

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VCAM1 antibody is un-conjugated

Application: Functional Studies (Func)

Clone: B-K9

Product Details anti-VCAM1 Antibody

Specificity: Recognises the Vascular Cellular Adhesion Molecule-1 (VCAM-1), a 110 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Activated human umbilical vein endothelial cells,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits cell attachment to VCAM-1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-VCAM1 antibody (ABIN1383722)

Cie?lik, Hrycek: "Pentraxin 3 as a biomarker of local inflammatory response to vascular injury in systemic lupus erythematosus." in: Autoimmunity, pp. 1-9, (2014) (PubMed).

Bompais, Chagraoui, Canron, Crisan, Liu, Anjo, Tolla-Le Port, Leboeuf, Charbord, Bikfalvi, Uzan: "Human endothelial cells derived from circulating progenitors display specific functional properties compared with mature vessel wall endothelial cells." in: Blood, Vol. 103, Issue 7, pp. 2577-84, (2004) (PubMed).

Ticchioni, Raimondi, Lamy, Wijdenes, Lindberg, Brown, Bernard: "Integrin-associated protein (CD47/IAP) contributes to T cell arrest on inflammatory vascular endothelium under flow." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 15, Issue 2, pp. 341-50, (2001) (PubMed).

Vermot-Desroches, Marchand, Roy, Wijdenes: "Heterogeneity of antigen expression among human umbilical cord vascular endothelial cells: identification of cell subsets by co-expression of haemopoietic antigens." in: Immunology letters, Vol. 48, Issue 1, pp. 1-9, (1996) (PubMed).

Target Details for VCAM1

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Alternative Name: CD106

Background: VCAM-1

Molecular Weight: 110 kDa

Pathways: Carbohydrate Homeostasis