CD3 antibody

Catalog No. ABIN1383795

This anti-CD3 antibody is a Mouse Monoclonal antibody detecting CD3 in FACS and Func. Suitable for Human. This Primary Antibody has been cited in 3+ publications.

Quick Overview for CD3 antibody (ABIN1383795)

Target: CD3

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: B-B11

Product Details anti-CD3 Antibody

Specificity: Recognises a 20-32 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: PHA activated T cells,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Biological Activity Comment: Induces T lymphocyte stimulation and proliferation

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-CD3 antibody (ABIN1383795)

Vermot-Desroches, Sergent, Bonnin, Wijdenes: "Characterization of monoclonal antibodies directed against trail or trail receptors." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).

Lu, Yu, Binder, Chen, Slepushkina, Rossi, Dropulic: "Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance." in: Journal of virology, Vol. 78, Issue 13, pp. 7079-88, (2004) (PubMed).

Dantal, Ninin, Hourmant, Boeffard, Cantarovich, Giral, Wijdenes, Soulillou, Le Mauff: "Anti-CD4 MoAb therapy in kidney transplantation--a pilot study in early prophylaxis of rejection." in: Transplantation, Vol. 62, Issue 10, pp. 1502-6, (1997) (PubMed).

Target Details for CD3

Target: CD3

Alternative Name: CD3

Molecular Weight: 20-32 kDa

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway