CD40 antibody

Catalog No. ABIN1383855

This anti-CD40 antibody is a Mouse Monoclonal antibody detecting CD40 in FACS. Suitable for Human. This Primary Antibody has been cited in 3+ publications.

Quick Overview for CD40 antibody (ABIN1383855)

Target: CD40

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD40 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: B-B20

Product Details anti-CD40 Antibody

Specificity: Recognises the Bp50 antigen, a 48 kDa protein

Purification: Ion exchange chromatography

Immunogen: Raji cell line,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Application Details

Application Notes: Use 10 μL to label 10^6 cells or 100 μL of whole blood

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-CD40 antibody (ABIN1383855)

Spirig, van Kooten, Obregon, Nicod, Daha, Rieben: "The complement inhibitor low molecular weight dextran sulfate prevents TLR4-induced phenotypic and functional maturation of human dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 2, pp. 878-90, (2008) (PubMed).

Moutaftsi, Mehl, Borysiewicz, Tabi: "Human cytomegalovirus inhibits maturation and impairs function of monocyte-derived dendritic cells." in: Blood, Vol. 99, Issue 8, pp. 2913-21, (2002) (PubMed).

Vermot-Desroches, Marchand, Roy, Wijdenes: "Heterogeneity of antigen expression among human umbilical cord vascular endothelial cells: identification of cell subsets by co-expression of haemopoietic antigens." in: Immunology letters, Vol. 48, Issue 1, pp. 1-9, (1996) (PubMed).

Target Details for CD40

Target: CD40

Alternative Name: CD40

Molecular Weight: 48 kDa

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints