IL-12p35+p70 antibody

Catalog No. ABIN1383950

The Mouse Monoclonal anti- antibody has been validated for ELISA and Func. It is suitable to detect in samples from Human. There is 1 publication available.

Quick Overview for IL-12p35+p70 antibody (ABIN1383950)

Target: IL-12p35+p70

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: ELISA, Functional Studies (Func)

Clone: B-T21

Product Details

Specificity: Recognises both natural and recombinant human IL-12 p35 + p70

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Recombinant human IL-12,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits IL-12 induced IFNg synthesis on PHA activated lymphocytes

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References

Nagai, Devergne, Mueller, Perkins, van Seventer, van Seventer: "Timing of IFN-beta exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: a role for IFN-beta-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation" in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 10, pp. 5233-43, (2003) (PubMed).

Target Details

Target: IL-12p35+p70

Background: IL-12p35/p70