TAS2R60 antibody (AA 41-140)

Catalog No. ABIN1385223

The Rabbit Polyclonal anti-TAS2R60 antibody (ABIN1385223) specifically detects TAS2R60 in WB, ELISA, ICC, IF (cc), IF (p), IHC (fro) and IHC (p). The antibody is reactive with Mouse samples.

Quick Overview for TAS2R60 antibody (AA 41-140) (ABIN1385223)

Target: TAS2R60 (Taste Receptor, Type 2, Member 60 (TAS2R60))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAS2R60 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TAS2R60 Antibody

Binding Specificity: AA 41-140

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Bee

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human T2R60

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TAS2R60

Target: TAS2R60 (Taste Receptor, Type 2, Member 60 (TAS2R60))

Alternative Name: T2R60

Background:

Synonyms: T2R56, TAS2R60, Taste receptor type 2 member 60, T2R60_HUMAN.

Background: T2R60 is a 318 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. T2R60 acts as a receptor that may play a role in the perception of bitterness, and is also thought to be involved in sensing the chemical composition of gastrointestinal content. As a gustducin-linked receptor, the activity of T2R60 may stimulate G alpha (alpha gustducin), mediate PLC beta 2 activation and lead to the gating of TRPM5. While expressed in subsets of taste receptor cells of the tongue and palate epithelium, T2R60 is found exclusively in gustducin-positive cells. The gene that encodes T2R60 contains 957 bases and maps to human chromosome 7q35. Chromosome 7 houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.