POTEG antibody (AA 151-250)

Catalog No. ABIN1385325

This anti-POTEG antibody is a Rabbit Polyclonal antibody detecting POTEG in WB, IF (cc), IF (p), ICC, ELISA, IHC (fro) and IHC (p). Suitable for Human.

Quick Overview for POTEG antibody (AA 151-250) (ABIN1385325)

Target: POTEG (POTE Ankyrin Domain Family, Member G (POTEG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POTEG antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-POTEG Antibody

Binding Specificity: AA 151-250

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ACTBL1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for POTEG

Target: POTEG (POTE Ankyrin Domain Family, Member G (POTEG))

Alternative Name: ACTBL1

Background:

Synonyms: ACTBL1, ovary, testis-expressed protein on chromosome 22, A26C3, Actin, beta like 1, ANKRD26 like family C, member 3, ANKRD26-like family C member 3, Cancer/testis antigen family 104, member 7, CT104.7, LA16c 3G11.6, POTE 22, POTE ankyrin domain family member H, POTE ankyrin domain family, member H, POTE-22, POTE22, POTEH, POTEH_HUMAN, Prostate, Prostate, ovary, testis expressed protein on chromosome 22, protein expressed in prostate, ovary, testis, and placenta 22, protein expressed in prostate, ovary, testis, and placenta POTE14 like.

Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5 % of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.