SPAC7 antibody
Quick Overview for SPAC7 antibody (ABIN1385436)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human SPAC7/C13ORF28
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Isotype
- IgG
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Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- SPAC7
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Background
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Synonyms: Chromosome 13 open reading frame 28, FLJ27356, Protein SPACA7, SPAC7_HUMAN, Spaca7, Sperm acrosome-associated protein 7.
Background: Comprising nearly 4 % of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. The C13orf28 gene product has been provisionally designated C13orf28 pending further characterization.
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Gene ID
- 122258
Target
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