C2orf57 antibody

Catalog No. ABIN1385500

This Rabbit Polyclonal antibody specifically detects C2orf57 in WB, IF (p) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for C2orf57 antibody (ABIN1385500)

Target: C2orf57 (Chromosome 2 Open Reading Frame 57 (C2orf57))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C2orf57 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C2orf57 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2orf57

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C2orf57

Target: C2orf57 (Chromosome 2 Open Reading Frame 57 (C2orf57))

Alternative Name: C2orf57

Background:

Synonyms: Chromosome 2 open reading frame 57, Hypothetical protein LOC165100, MGC35154, Uncharacterized protein C2orf57, CB057_HUMAN.

Background: C2orf57, also known as MGC35154, is a 395 amino acid protein encoded by a gene that maps to human chromosome 2q37.1. As the second largest human chromosome, chromosome 2 makes up approximately 8 % of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

Gene ID: 165100