WDFY3 antibody

Catalog No. ABIN1385528

The Rabbit Polyclonal anti-WDFY3 antibody is suitable to detect WDFY3 in samples from Human, Mouse and Rat. It has been validated for IF (p) and IHC (p).

Quick Overview for WDFY3 antibody (ABIN1385528)

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDFY3 antibody is un-conjugated

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-WDFY3 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WDFY3

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for WDFY3

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Alternative Name: WDFY3

Background:

Synonyms: Alfy, Autophagy linked FYVE protein, KIAA0993, MGC16461, WD repeat and FYVE domain containing 3, ZFYVE25, WDFY3_HUMAN.

Background: WDFY3 was identified in a screen for phosphatidylinositol 3 phosphate binding proteins. The FYVE domain is a zinc binding domain found in many PtdIns binding proteins and is proposed to target proteins to membrane lipids. WDFY3 has been shown localized to the nuclear membrane and within autophagic membranes and it is proposed to function as a link between protein aggregates and the autophagic machinery. WDFY3 is also known as autophagy linked FYVE protein.

Gene ID: 23001