C12ORF54 antibody

Catalog No. ABIN1385540

The Rabbit Polyclonal anti-C12ORF54 antibody has been validated for WB, IF (p) and IHC (p). It is suitable to detect C12ORF54 in samples from Human, Mouse and Rat.

Quick Overview for C12ORF54 antibody (ABIN1385540)

Target: C12ORF54 (Chromosome 12 Open Reading Frame 54 (C12ORF54))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C12ORF54 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C12ORF54 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C12ORF54

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C12ORF54

Target: C12ORF54 (Chromosome 12 Open Reading Frame 54 (C12ORF54))

Alternative Name: C12ORF54

Background:

Synonyms: MGC35033, C12orf54, Chromosome 12 open reading frame 54, CL054_HUMAN, HSD 29, HSD 30, HSD29, Uncharacterized protein C12orf54.

Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf54 gene product has been provisionally designated C12orf54 pending further characterization.

Gene ID: 121273