DPP8 antibody (AA 301-400)

Catalog No. ABIN1385761

This Rabbit Polyclonal antibody specifically detects DPP8 in WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro). It exhibits reactivity toward Human.

Quick Overview for DPP8 antibody (AA 301-400) (ABIN1385761)

Target: DPP8 (Dipeptidyl-Peptidase 8 (DPP8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPP8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DPP8 Antibody

Binding Specificity: AA 301-400

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DPP8/DPRP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DPP8

Target: DPP8 (Dipeptidyl-Peptidase 8 (DPP8))

Alternative Name: Dpp8

Background:

Synonyms: Dipeptidyl peptidase 8, Dipeptidyl peptidase IV-related protein 1, Dipeptidyl peptidase VIII, DP8, DPRP-1, EC 3.4.14.5, Prolyl dipeptidase DPP8, DPP8_HUMAN.

Background: Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPRP1 (dipeptidyl-peptidase IV-related protein 1), also known as DPP8 (dipeptidyl-peptidase 8), DP8 or MSTP141, is a member of the peptidase S9B family of proteins that exhibit prolyl oligopeptidase activity. DPRP1 localizes to the cytoplasm and is ubiquitously expressed with predominant expression in placenta, brain, prostate, testis and muscle. DPRP1 is similar to CD26 (dipeptidyl peptidase IV) suggesting that it may be involved in immune function and participate in the activation of T-cells.

Gene ID: 54878