TCF12 antibody (AA 51-150)

Catalog No. ABIN1385824

This Rabbit Polyclonal antibody specifically detects TCF12 in WB, ELISA, IF (cc), IF (p), IHC (p), ICC and IHC (fro). It exhibits reactivity toward Human and Ratand has been mentioned in 1 publication.

Quick Overview for TCF12 antibody (AA 51-150) (ABIN1385824)

Target: TCF12 (Transcription Factor 12 (TCF12))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TCF12 Antibody

Binding Specificity: AA 51-150

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Sheep,Horse,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TCF12

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TCF12 antibody (ABIN1385824)

Li, Leng, Liu, Hu, Zhang, Li, Jiang, Zhou, Xu: "Overexpressed PTOV1 associates with tumorigenesis and progression of esophageal squamous cell carcinoma." in: Tumour biology, Vol. 39, Issue 6, pp. 1010428317705010, (2017) (PubMed).

Target Details for TCF12

Target: TCF12 (Transcription Factor 12 (TCF12))

Alternative Name: TCF12/HEB

Background:

Synonyms: bHLHb20, Class B basic helix-loop-helix protein 20, DNA binding protein HTF4, DNA-binding protein HTF4, E box binding protein, E-box-binding protein, HEB, HTF4, HTF4_HUMAN, TCF-12, Tcf12, Transcription factor 12, Transcription factor HTF-4, Transcription factor HTF4.

Background: Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.

Gene ID: 6938

UniProt: Q99081

Pathways: SARS-CoV-2 Protein Interactome