SFRS7 antibody (AA 2-70)

Catalog No. ABIN1385828

The Rabbit Polyclonal anti-SFRS7 antibody is suitable to detect SFRS7 in samples from Rat. It has been validated for ELISA, IHC (p), IF (cc), IF (p), ICC and IHC (fro).

Quick Overview for SFRS7 antibody (AA 2-70) (ABIN1385828)

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRS7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SFRS7 Antibody

Binding Specificity: AA 2-70

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Chicken,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SFRS7

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SFRS7

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Alternative Name: SFRS7/9G8/SRp20

Background:

Synonyms: 9G8, AAG3, SFRS7, Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7

Background: Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.

Gene ID: 6432

UniProt: Q16629