ATP2B2 antibody (AA 361-460)

Catalog No. ABIN1385852

The Rabbit Polyclonal anti-ATP2B2 antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). It is suitable to detect ATP2B2 in samples from Mouse and Rat. There is 1 publication available.

Quick Overview for ATP2B2 antibody (AA 361-460) (ABIN1385852)

Target: ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP2B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ATP2B2 Antibody

Binding Specificity: AA 361-460

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PMCA

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ATP2B2 antibody (ABIN1385852)

Schmidt, Kollewe, Constantin, Henrich, Ritzau-Jost, Bildl, Saalbach, Hallermann, Kulik, Fakler, Schulte: "Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance." in: Neuron, Vol. 96, Issue 4, pp. 827-838.e9, (2017) (PubMed).

Target Details for ATP2B2

Target: ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))

Alternative Name: PMCA2

Background:

Synonyms: PMCA2, PMCA2a, PMCA2i, Plasma membrane calcium-transporting ATPase 2, Plasma membrane calcium ATPase isoform 2, Plasma membrane calcium pump isoform 2, ATP2B2

Background: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.

Gene ID: 491

UniProt: Q01814

Pathways: Sensory Perception of Sound, Regulation of Cell Size, Ribonucleoside Biosynthetic Process