Cytochrome B Reductase 1 antibody (AA 51-150)

Catalog No. ABIN1386135

This anti-Cytochrome B Reductase 1 antibody is a Rabbit Polyclonal antibody detecting Cytochrome B Reductase 1 in ELISA, WB, IHC (p), IF (cc), IF (p) and IHC (fro). Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Cytochrome B Reductase 1 antibody (AA 51-150) (ABIN1386135)

Target: Cytochrome B Reductase 1 (CYBRD1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytochrome B Reductase 1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Cytochrome B Reductase 1 Antibody

Binding Specificity: AA 51-150

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CYBR1/Cytochrome b reductase 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Cytochrome B Reductase 1 antibody (ABIN1386135)

Rychtarcikova, Lettlova, Tomkova, Korenkova, Langerova, Simonova, Zjablovskaja, Alberich-Jorda, Neuzil, Truksa: "Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism." in: Oncotarget, Vol. 8, Issue 4, pp. 6376-6398, (2016) (PubMed).

Target Details for Cytochrome B Reductase 1

Target: Cytochrome B Reductase 1 (CYBRD1)

Background:

Synonyms: DCYTB, FRRS3, CYB561A2, Cytochrome b reductase 1, Duodenal cytochrome b, Ferric-chelate reductase 3, CYBRD1

Background: Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells.

Gene ID: 79901

UniProt: Q53TN4

Pathways: Transition Metal Ion Homeostasis