NCR1 antibody (AA 198-206)

Catalog No. ABIN1386154

This Rabbit Polyclonal antibody specifically detects NCR1 in WB, ELISA and IHC (p). It exhibits reactivity toward Human and Mouse and has been mentioned in 3+ publications.

Quick Overview for NCR1 antibody (AA 198-206) (ABIN1386154)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NCR1 Antibody

Binding Specificity: AA 198-206

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD335

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-NCR1 antibody (ABIN1386154)

Jaime-Ramirez, Yu, Caserta, Yoo, Zhang, Lee, Hofmeister, Lee, Kumar, Pan, Kumar, Baiocchi, Teknos, Pichiorri, Kaur, Old: "Reolysin and Histone Deacetylase Inhibition in the Treatment of Head and Neck Squamous Cell Carcinoma." in: Molecular therapy oncolytics, Vol. 5, pp. 87-96, (2017) (PubMed).

Pan, Kang, Wang, Liu, Oshima, Huang, Zhang, Yearsley, Yu, Wang: "Black Raspberries Enhance Natural Killer Cell Infiltration into the Colon and Suppress the Progression of Colorectal Cancer." in: Frontiers in immunology, Vol. 8, pp. 997, (2017) (PubMed).

Vindevogel, Baert, VAN Hoylandt, Verbist, Vande Velde, Garg, Agostinis, Vergote, Coosemans: "The Use of Toll-like Receptor 4 Agonist to Reshape the Immune Signature in Ovarian Cancer." in: Anticancer research, Vol. 36, Issue 11, pp. 5781-5792, (2016) (PubMed).

Target Details for NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Alternative Name: NCR1

Background:

Synonyms: LY94, CD335, NKP46, NK-p46, Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, hNKp46, NCR1

Background: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Gene ID: 9437

UniProt: O76036

Pathways: Regulation of Leukocyte Mediated Immunity