VAT1L antibody (AA 321-419)

Catalog No. ABIN1386227

The Rabbit Polyclonal anti-VAT1L antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It is suitable to detect VAT1L in samples from Rat.

Quick Overview for VAT1L antibody (AA 321-419) (ABIN1386227)

Target: VAT1L (Vesicle Amine Transport 1-Like (VAT1L))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAT1L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-VAT1L Antibody

Binding Specificity: AA 321-419

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VAT1L/KIAA1576

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for VAT1L

Target: VAT1L (Vesicle Amine Transport 1-Like (VAT1L))

Alternative Name: VAT1L/KIAA1576

Background:

Synonyms: Probable oxidoreductase KIAA1576, Synaptic vesicle membrane protein VAT 1 homolog like, Synaptic vesicle membrane protein VAT-1 homolog-like, VAT 1L, VAT1L, VAT1L_HUMAN, Vesicle amine transport protein 1 homolog T. calornica like.

Background: Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3 % of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The KIAA1576 gene product has been provisionally designated KIAA1576 pending further characterization.

Gene ID: 3384