TPM1/2/3/4 (AA 210-260) antibody

Catalog No. ABIN1386303

The Rabbit Polyclonal anti-TPM1/2/3/4 antibody (ABIN1386303) specifically detects TPM1/2/3/4 in IF (p), IHC (p) and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TPM1/2/3/4 (AA 210-260) antibody (ABIN1386303)

Target: TPM1/2/3/4

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Product Details

Binding Specificity: AA 210-260

Specificity: This antibody will detect all 4 Tropomyosin proteins: TPM1, TPM2, TPM3, and TPM4

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TPM1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details

Target: TPM1/2/3/4

Background:

Synonyms: TPM1, Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1, C15orf13, TMSA, TPM2, Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2, TMSB, TPM3, Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3, TPM4, Tropomyosin alpha-4 chain, TM30p1, Tropomyosin-4

Background: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.

Gene ID: 7168

UniProt: P09493