Plexin B3 antibody (AA 354-400)

Catalog No. ABIN1386311

The Rabbit Polyclonal anti-Plexin B3 antibody has been validated for IF (cc), IF (p), ELISA, IHC (fro), IHC (p) and ICC. It is suitable to detect Plexin B3 in samples from Mouse.

Quick Overview for Plexin B3 antibody (AA 354-400) (ABIN1386311)

Target: Plexin B3 (PLXNB3)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin B3 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-Plexin B3 Antibody

Binding Specificity: AA 354-400

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Plexin B2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Plexin B3

Target: Plexin B3 (PLXNB3)

Alternative Name: Plexin B3

Background:

Synonyms: PLEXR, PLXN6, PLEXB3, Plexin-B3, PLXNB3, KIAA1206

Background: Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1.

Gene ID: 5365

UniProt: Q9ULL4