ATRAID antibody

Catalog No. ABIN1386345

This anti-ATRAID antibody is a Rabbit Polyclonal antibody detecting ATRAID in WB, IF (p) and IHC (p). Suitable for Human, Rat and Mouse.

Quick Overview for ATRAID antibody (ABIN1386345)

Target: ATRAID (All-Trans Retinoic Acid-Induced Differentiation Factor (ATRAID))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATRAID antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ATRAID Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2orf28

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ATRAID

Target: ATRAID (All-Trans Retinoic Acid-Induced Differentiation Factor (ATRAID))

Alternative Name: C2orf28

Background:

Synonyms: Apoptosis related protein 3, Apoptosis related protein APR 3, APR 3, APR3, Chromosome 2 open reading frame 28, HSPC013, p18, PRO240, ARAID_HUMAN.

Background: APR3, also known as C2orf28 or p18, is a 229 amino acid single-pass membrane protein that contains one EGF-like domain and exists as two alternatively spliced isoforms. Expressed at a low level in hematopoietic cell lines, APR3 is thought to be involved in apoptosis and may also play a role in hematopoietic development and differentiation. The gene encoding APR3 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8 % of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstr syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.