ERC2 antibody (AA 361-460)

Catalog No. ABIN1386524

The Rabbit Polyclonal anti-ERC2 antibody is suitable to detect ERC2 in samples from Human. It has been validated for WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC.

Quick Overview for ERC2 antibody (AA 361-460) (ABIN1386524)

Target: ERC2 (ELKS/RAB6-Interacting/CAST Family Member 2 (ERC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-ERC2 Antibody

Binding Specificity: AA 361-460

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CAST1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ERC2

Target: ERC2 (ELKS/RAB6-Interacting/CAST Family Member 2 (ERC2))

Alternative Name: ERC2/CAST1

Background:

Synonyms: Cast, CAST1, CAZ-associated structural protein 1, Cmbp gene name, Cytomatrix protein p110, ERC protein 2, KIAA0378, ERC2_HUMAN.

Background: ERCs (ERC1 and ERC2) also referred to as ELKS and CAST are related proteins which share an identical C-terminal sequence. They interact with the conserved RIM PDZ domain via an unusual PDZ binding motif. ERC2/CAST 1 is only expressed as a single RIM binding variant. All ERCs have been shown to interact with Rab6, a protein involved in membrane trafficking at the Golgi complex. The function of these proteins has not been determined yet. They may link Rab6 mediated non-neuronal membrane traffic at the Golgi complex to neuronal membrane traffic at the active zone executed via RIMs.