RIMS4 antibody (AA 1-100)

Catalog No. ABIN1386533

The Rabbit Polyclonal anti-RIMS4 antibody is suitable to detect RIMS4 in samples from Human. It has been validated for WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC.

Quick Overview for RIMS4 antibody (AA 1-100) (ABIN1386533)

Target: RIMS4 (Regulating Synaptic Membrane Exocytosis 4 (RIMS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIMS4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-RIMS4 Antibody

Binding Specificity: AA 1-100

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RIMS4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RIMS4

Target: RIMS4 (Regulating Synaptic Membrane Exocytosis 4 (RIMS4))

Alternative Name: RIMS4

Background:

Synonyms: C20orf190, dJ781B1.3, Rab3-interacting molecule 4, regulating synaptic membrane exocytosis 4, Regulating synaptic membrane exocytosis protein 4, RIM 4, RIM4 gamma, Rims4, RIMS4_HUMAN.

Background: Rim4 (Rab 3 interacting molecule 4), also known as Rim4 or regulating synaptic membrane exocytosis protein 4, is a 269 amino acid protein that localizes to the cell junction and regulates synaptic membrane exocytosis.Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis. Rab 3 functions in an inhibitory capacity by controlling the recruitment of secretory vesicles into a releasable pool at the plasma membrane. Rim (Rab 3 interacting molecule), a putative effector protein for Rab 3 proteins, is thought to regulate neutrotransmitter release through its interaction with Rab 3 and other synaptic proteins.

Gene ID: 140730

Pathways: Synaptic Vesicle Exocytosis