KIRREL3 antibody (AA 351-450)

Catalog No. ABIN1386589

This Rabbit Polyclonal antibody specifically detects KIRREL3 in ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. It exhibits reactivity toward Mouse.

Quick Overview for KIRREL3 antibody (AA 351-450) (ABIN1386589)

Target: KIRREL3 (Kin of IRRE Like 3 (KIRREL3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIRREL3 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-KIRREL3 Antibody

Binding Specificity: AA 351-450

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KIRREL3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KIRREL3

Target: KIRREL3 (Kin of IRRE Like 3 (KIRREL3))

Alternative Name: KIRREL3

Background:

Synonyms: Kin of IRRE like 3 Drosophila, Kin of IRRE like 3, Kin of irregular chiasm like protein 3 , KIRRE, KIRREL 3, KIRREL-3, MRD4, NEPH2, Nephrin like 2, PRO19814, PRO4502, yUNQ5923, KIRR3_HUMAN.

Background: NEPH2 is a 778 amino acid single-pass type I membrane protein that belongs to the nephrin-like protein family and immunoglobulin superfamily. Expressed in both fetal and adult brain, as well as podocytes of kidney glomeruli, NEPH2 contains five Ig-like C2-type (immunoglobulin-like) domains and is thought to plaly a role in the hematopoetic supportive capacity of stroma cells. NEPH2 undergoes alternative splicing to produce two isoforms and contains a C-terminal cytoplasmic domain which it uses to interact with Podocin, a podocyte protein involved in ultrafiltration. Defects in the gene encoding NEPH2 are associated with mental retardation autosomal dominant type 4 (MRD4).