FAM81A antibody (AA 281-368)

Catalog No. ABIN1386875

The Rabbit Polyclonal anti-FAM81A antibody has been validated for IF (cc), IF (p), ELISA, IHC (fro), IHC (p) and ICC. It is suitable to detect FAM81A in samples from Human.

Quick Overview for FAM81A antibody (AA 281-368) (ABIN1386875)

Target: FAM81A (Family with Sequence Similarity 81, Member A (FAM81A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM81A antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-FAM81A Antibody

Binding Specificity: AA 281-368

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM81A

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FAM81A

Target: FAM81A (Family with Sequence Similarity 81, Member A (FAM81A))

Alternative Name: FAM81A

Background:

Synonyms: FA81B_HUMAN, FAM81B, Family with sequence similarity 81, member B, FLJ25333, Hypothetical protein LOC153643, Protein FAM81B.

Background: Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3 % of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene. The FAM81A gene product has been provisionally designated FAM81A pending further characterization.

Gene ID: 145773