IQCK antibody

Catalog No. ABIN1386891

This anti-IQCK antibody is a Rabbit Polyclonal antibody detecting IQCK in WB, IF (p) and IHC (p). Suitable for Human.

Quick Overview for IQCK antibody (ABIN1386891)

Target: IQCK (IQ Motif Containing K (IQCK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQCK antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IQCK Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IQCK

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IQCK

Target: IQCK (IQ Motif Containing K (IQCK))

Alternative Name: IQCK

Background:

Synonyms: FLJ20115, FLJ36575, IQ domain containing protein K, MGC35048, IQCK_HUMAN.

Background: Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3 % of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. alternatively splicing events.

Gene ID: 124152