RGC32 antibody (AA 98-137)

Catalog No. ABIN1386922

This Rabbit Polyclonal antibody specifically detects RGC32 in WB, IF (p) and IHC (p). It exhibits reactivity toward Human, Mouse and Ratand has been mentioned in 1 publication.

Quick Overview for RGC32 antibody (AA 98-137) (ABIN1386922)

Target: RGC32 (C13orf15) (Chromosome 13 Open Reading Frame 15 (C13orf15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGC32 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RGC32 Antibody

Binding Specificity: AA 98-137

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RGC32

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-RGC32 antibody (ABIN1386922)

Vlaicu, Tatomir, Boodhoo, Ito, Fosbrink, Cudrici, Mekala, Ciriello, Crişan, Boţan, Rus, Rus: "RGC-32 is expressed in the human atherosclerotic arterial wall: Role in C5b-9-induced cell proliferation and migration." in: Experimental and molecular pathology, Vol. 101, Issue 2, pp. 221-230, (2016) (PubMed).

Target Details for RGC32

Target: RGC32 (C13orf15) (Chromosome 13 Open Reading Frame 15 (C13orf15))

Alternative Name: RGC32

Background:

Synonyms: RGC32, RGC-32, C13orf15, bA157L14.2, Regulator of cell cycle RGCC, Response gene to complement 32 protein, RGCC

Background: Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.

Gene ID: 28984

UniProt: Q9H4X1