ATAD2 antibody (AA 1025-1063)

Catalog No. ABIN1386935

The Rabbit Polyclonal anti-ATAD2 antibody has been validated for IF (p) and IHC (p). It is suitable to detect ATAD2 in samples from Human, Mouse and Rat.

Quick Overview for ATAD2 antibody (AA 1025-1063) (ABIN1386935)

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATAD2 antibody is un-conjugated

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ATAD2 Antibody

Binding Specificity: AA 1025-1063

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATAD2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ATAD2

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Alternative Name: ATAD2

Background:

Synonyms: ANCCA, CT137, PRO2000, ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated protein, ATAD2, L16

Background: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.

Gene ID: 29028

UniProt: Q6PL18