DDX5 antibody (AA 301-430)

Catalog No. ABIN1387377

This anti-DDX5 antibody is a Rabbit Polyclonal antibody detecting DDX5 in WB and ELISA. Suitable for Mouse.

Quick Overview for DDX5 antibody (AA 301-430) (ABIN1387377)

Target: DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DDX5 Antibody

Binding Specificity: AA 301-430

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DDX5/p68 RNA Helicase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DDX5

Target: DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Alternative Name: DDX5

Background:

Synonyms: ATP dependent RNA helicase DDX5, DDX 5, Ddx5, DDX5_HUMAN, DEAD Asp Glu Ala Asp box helicase 5, DEAD Asp Glu Ala Asp box polypeptide 5, DEAD box 5, DEAD box protein 5, DEAD/H Asp Glu Ala Asp/His box polypeptide 5 RNA helicase, 68kD, DEAD/H Asp Glu Ala Asp/His box polypeptide 5, DEAD/H Asp-Glu-Ala-Asp/His box polypeptide 5 RNA helicase 68 kDa, DEAD/H box-5 RNA helicase 68kD, DKFZp686J01190, G17P1, HELR, HLR 1, HLR1, HUMP68, P68, P68, p68 RNA helicase, Probable ATP dependent RNA helicase DDX5, Probable ATP-dependent RNA helicase DDX5, RNA helicase 68kD, RNA helicase p68, RNA-dependent ATPase.

Background: p68 RNA helicase is a nuclear protein that exhibits RNA-dependent ATPase activity. Phosphorylation by protein kinase C inhibits p68 RNA helicase activity. p68 RNA helicase appears to play a role in organ differentiation during development. Furthermore, p68 RNA helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos. At the cellular level, the expression levels of p68 RNA helicase increases in serum-induced quiescent cell lines. p68 RNA helicase may function as a coactivator for estrogen receptor alpha. Additionally, p68 RNA helicase associates with transcriptional coactivators CBP and p300. p68 RNA helicase localizes to the nucleus under normal conditions. During late telophase, p68 RNA helicase and fibrillarin colocalize to nascent nucleoli. p68 RNA helicase may function as a heterodimer with p72 RNA helicase.

Gene ID: 1655

UniProt: P17844

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus