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TROVE2 antibody (AA 331-430)

The Rabbit Polyclonal anti-TROVE2 antibody has been validated for ELISA, IF (cc), IF (p), ICC, IHC (p) and IHC (fro). It is suitable to detect TROVE2 in samples from Human.
Catalog No. ABIN1387451

Quick Overview for TROVE2 antibody (AA 331-430) (ABIN1387451)

Target

See all TROVE2 Antibodies
TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

Reactivity

  • 77
  • 14
  • 8
  • 7
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Host

  • 73
  • 5
  • 1
Rabbit

Clonality

  • 75
  • 4
Polyclonal

Conjugate

  • 42
  • 6
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TROVE2 antibody is un-conjugated

Application

  • 48
  • 30
  • 23
  • 12
  • 12
  • 9
  • 8
  • 7
  • 7
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

    • 14
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-430

    Predicted Reactivity

    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human TROVE-2/SSA2

    Isotype

    IgG
  • Application Notes

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Expiry Date

    12 months
  • Target

    TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

    Alternative Name

    TROVE-2

    Background

    Synonyms: TROVE2, 60 kDa ribonucleoprotein Ro, 60 kDa Ro protein, 60 kDa SS A/Ro ribonucleoprotein, 60 kDa SS-A/Ro ribonucleoprotein, Autoantigen Ro/SSA, 60-KD, bA101E13.2, Gastric cancer multi drug resistance protein, Ribonucleoprotein autoantigen SS A/Ro, RO 60, Ro 60 kDa autoantigen, RO60, RO60_HUMAN, RoRNP, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, Sjogren syndrome antigen A2 60kD ribonucleoprotein autoantigen SS A/Ro, Sjogren syndrome antigen A2 60 kDa ribonucleoprotein autoantigen SS A/Ro, Sjogren syndrome antigen A2, SS A, SS-A, SS-A/Ro, SSA 2, SSA, SSA2, TROVE 2, TROVE domain family member 2, TROVE2.

    Background: Ro autoantigens are of clinical significance because directed against them are found in most patients with primary Sjqgren syndrome, subacute cutaneous lupus erythematosus (SLE), neonatal lupus erythematosus, ANA-negative lupus erythematosus, and systemic lupus erythematosus-like disease secondary to homozygous C2 or C4 complement deficiency (1). Ro/SSA is a ribonucleoprotein that binds to auto in 35 to 50 % of patients with SLE and in up to 97 % of patients with Sjqgren syndrome (2). The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules (2). Most anti-Ro/SSA-positive sera detect not only the main protein, but also a smaller Ro/SSA protein (2). The genes which encode the smaller and larger proteins map to human chromosomes 11p15.5 and 1q31, respectively (3?). La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with auto from patients with Sjren syndrome and SLE (6).

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