KLF7 antibody (AA 131-210)

Catalog No. ABIN1387653

This anti-KLF7 antibody is a Rabbit Polyclonal antibody detecting KLF7 in ELISA, WB, ICC, IHC (p), IF (cc), IF (p) and IHC (fro). Suitable for Mouse.

Quick Overview for KLF7 antibody (AA 131-210) (ABIN1387653)

Target: KLF7 (Kruppel-Like Factor 7 (Ubiquitous) (KLF7))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF7 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-KLF7 Antibody

Binding Specificity: AA 131-210

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLF7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KLF7

Target: KLF7 (Kruppel-Like Factor 7 (Ubiquitous) (KLF7))

Alternative Name: KLF7

Background:

Synonyms: KLF7, KLF7_HUMAN, Krueppel like factor 7, Krueppel-like factor 7, Kruppel like factor 7 , Ubiquitous krueppel like factor, Ubiquitous krueppel-like factor, UKLF.

Background: KLF7 is a transcriptional activator that belongs to the Kr_ppel C2H2-type zinc finger protein family. KLF7 targets promotor regions bearing CACCC elements in order to regulate transcription. It is believed that KLF7 is an important element for regulation of differentiation and the development of nervous systems. Specifically, increased expression of KLF7 is associated with neuronal precursors exiting the cell cycle and beginning to differentiate. Overexpression of KLF7 can lead to cell cycle arrest and a decrease in DNA synthesis. Also, KLF7 is thought to regulate the expression of Trk A, the receptor for nerve growth factor, which is required for the normal growth and maturation of neurons. KLF7 is a widely expressed protein with highest expression found in brain and nervous tissue.