KCTD12 antibody (AA 251-325)

Catalog No. ABIN1387670

The Rabbit Polyclonal anti-KCTD12 antibody is suitable to detect KCTD12 in samples from Human. It has been validated for ELISA, IHC (p), ICC, IF (cc), IF (p) and IHC (fro).

Quick Overview for KCTD12 antibody (AA 251-325) (ABIN1387670)

Target: KCTD12 (Potassium Channel Tetramerisation Domain Containing 12 (KCTD12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD12 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-KCTD12 Antibody

Binding Specificity: AA 251-325

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCTD12

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KCTD12

Target: KCTD12 (Potassium Channel Tetramerisation Domain Containing 12 (KCTD12))

Alternative Name: KCTD12

Background:

Synonyms: C13orf2, BTB/POZ domain-containing protein KCTD12, C13orf2, KCD12_HUMAN, KCTD12, KIAA1778, PFET1, Pfetin, potassium channel tetramerisation domain containing 12 USA, Predominantly fetal expressed T1 domain.

Background: The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (POxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD12 (potassium channel tetramerisation domain containing 12), also known as PFET1 or PFETIN, is a 325 amino acid protein that is expressed in fetal organs, with highest levels in the cochlea and brain and extremely low levels in adult organs, such as brain and lung. KCTD12 is considered a prognostic biomarker of gastrointestinal stromal tumors.

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling