HS6ST1 antibody

Catalog No. ABIN1387825

This Rabbit Polyclonal antibody specifically detects HS6ST1 in WB, IF (p) and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HS6ST1 antibody (ABIN1387825)

Target: HS6ST1 (Heparan Sulfate 6-O-Sulfotransferase 1 (HS6ST1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HS6ST1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HS6ST1 Antibody

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HS6ST1

Isotype: IgG

Application Details

Application Notes: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C

Expiry Date: 12 months

Target Details for HS6ST1

Target: HS6ST1 (Heparan Sulfate 6-O-Sulfotransferase 1 (HS6ST1))

Alternative Name: Hs6st1

Background:

Heparan sulfate structures, which are responsible for executing multiple biologic activities, are generated and regulated by heparan sulfate (HS) biosynthetic enzymes. HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), also known as HS6ST, is a 411 amino acid single-pass type II membrane protein that exists as multiple alternatively spliced isoforms and belongs to the sulfotransferase 6 family. Expressed in fetal brain, HS6ST1 functions as a 6-O-sulfation enzyme that specifically catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the N-sulfoglucosamine residue (GlcNS) HS. HS6ST1 is subject to post-translational N-glycosylation and is encoded by a functional gene on human chromosome 2 and a pseudogene on human chromosome 1 (known as LOC728969).

Synonyms: 6OST 1, 6OST1, DKFZp547H098, FLJ25392, H6 ST1, H6ST 1, H6ST1_HUMAN, Heparan sulfate 6 O sulfotransferase 1, Heparan sulfate 6 sulfotransferase, Heparan sulphate 6 O sulphotransferase 1, Heparan-sulfate 6-O-sulfotransferase 1, HS6 ST1, HS6ST 1, HS6ST , HS6ST-1, HS6ST1, MGC116899, MGC116901.

Pathways: Glycosaminoglycan Metabolic Process