P2RY10 antibody (AA 151-250)

Catalog No. ABIN1387827

Product Details anti-P2RY10 Antibody

Target: P2RY10 (Purinergic Receptor P2Y, G-Protein Coupled, 10 (P2RY10))

Binding Specificity: AA 151-250

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY10 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human P2Y10

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for P2RY10

Target: P2RY10 (Purinergic Receptor P2Y, G-Protein Coupled, 10 (P2RY10))

Alternative Name: P2Y10 (P2RY10 Products)

Background:

Synonyms: G protein coupled purinergic receptor P2Y10, P2ry10, P2Y like receptor, P2Y purinoceptor 10, P2Y-like receptor, P2Y10, P2Y10_HUMAN, Purinergic receptor P2Y G protein coupled 10, Putative P2Y purinoceptor 10.

Background: Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation.

Gene ID: 27334

UniProt: O00398