Homeobox D13 antibody (AA 251-343)

Catalog No. ABIN1387917

This anti-Homeobox D13 antibody is a Rabbit Polyclonal antibody detecting Homeobox D13 in WB, ELISA, IHC (p), ICC, IF (cc), IF (p) and IHC (fro). Suitable for Human.

Quick Overview for Homeobox D13 antibody (AA 251-343) (ABIN1387917)

Target: Homeobox D13 (HOXD13)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Homeobox D13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Homeobox D13 Antibody

Binding Specificity: AA 251-343

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOXD13

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Homeobox D13

Target: Homeobox D13 (HOXD13)

Alternative Name: HOXD13

Background:

Synonyms: HOXD13, BDE, BDSD, Homeo box 4I, Homeo box D13, Homeo box protein Hox D13, Homeo box protein HoxD13, Homeobox 4I, Homeobox D13, Homeobox protein Hox D13, Homeobox protein Hox-D13, Homeobox protein HoxD13, Homeobox4I, HomeoboxD13, Hox 4I, HOX D13, Hox-4.8, Hox4I, HOXD 13, HoxD13, SPD, HXD13_HUMAN.

Background: The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. HoxD13 is a sequence-specific transcription factor that provides cells with specific positional identities on the anterior-posterior axis of developing mammals. Defects in HoxD13 are the cause of synpolydactyly (SPD). SPD is a limb malformation that shows a characteristic manifestation in both hands and feet. This condition is inherited as an autosomal dominant trait with reduced penetrance. Defects in HoxD13 are also the cause of brachydactyly type D and type E.

Gene ID: 3239

Pathways: Synaptic Membrane