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DUOXA1 antibody (Dual Oxidase Maturation Factor 1) Primary Antibody

DUOXA1 Reactivity: Human, Mouse, Rat IF (p), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387935
$339.90
Plus shipping costs $45.00
100 μL
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Delivery in 4 to 6 Business Days
  • Target
    DUOXA1
    Reactivity
    • 9
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 7
    • 2
    Rabbit
    Clonality
    • 9
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    This DUOXA1 antibody is un-conjugated
    Application
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DUOXA1
    Isotype
    IgG
  • Application Notes
    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Target
    DUOXA1
    Alternative Name
    Duoxa1 (DUOXA1 Antibody Abstract)
    Synonyms
    NIP, NUMBIP, mol, BC019755, Nip, Nip1, RGD1306601, dual oxidase maturation factor 2, dual oxidase maturation factor 1, DUOXA2, DUOXA1, LOC100405759, Duoxa1
    Background

    DUOXA1 is a 343 amino acid multi-pass membrane protein that belongs to the DUOXA family and exists as multiple alternatively spliced isoforms. Expressed almost exclusively in thyroid tissue, but also present in esophageal tissue, DUOXA1 interacts with NUMB and is thought to be essential for the maturation and transport of functional DUOX1 from the endoplasmic reticulum to the plasma membrane. The gene encoding DUOXA1 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

    Subcellular location: Extracellular

    Synonyms: DOXA1_HUMAN, Dual oxidase activator 1, Dual oxidase maturation factor 1, duoxa1, NIP, Numb interacting protein, Numb-interacting protein, NUMBIP.

    Gene ID
    90527
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