PTGER4 antibody (AA 151-250)

Catalog No. ABIN1387963

Product Details anti-PTGER4 Antibody

Target: PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))

Binding Specificity: AA 151-250

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGER4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EP4R/Prostaglandin E Receptor EP4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PTGER4 antibody (ABIN1387963)

Takemiya, Takeuchi, Kawakami: "Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4⁺ T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis." in: International journal of molecular sciences, Vol. 18, Issue 12, (2018) (PubMed).

Koyama, Iwakura, Dote, Bando, Hosoda, Ariyasu, Kusakabe, Son, Hosoda, Akamizu, Kangawa, Nakao: "Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells." in: Endocrinology, Vol. 157, Issue 2, pp. 692-704, (2016) (PubMed).

Hu, Xi, Cao, Yang, Liu, Sheng, Han, Yuan, Guo, Weng, Xu: "The expression of prostaglandin-E2 and its receptor in the oviduct of Chinese brown frog (Rana dybowskii)." in: Prostaglandins & other lipid mediators, Vol. 124, pp. 9-15, (2016) (PubMed).

Target Details for PTGER4

Target: PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))

Abstract: PTGER4 Products

Background:

Synonyms: EP4, EP4R, Prostaglandin E2 receptor EP4 subtype, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostanoid EP4 receptor, PTGER4, PTGER2

Background: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

Gene ID: 5734

UniProt: P35408