MYBPC1 antibody (AA 51-150) (AbBy Fluor® 488)

Catalog No. ABIN1388878

This Rabbit Polyclonal antibody specifically detects MYBPC1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for MYBPC1 antibody (AA 51-150) (AbBy Fluor® 488) (ABIN1388878)

Target: MYBPC1 (Myosin Binding Protein C, Slow Type (MYBPC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBPC1 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MYBPC1 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 51-150

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MYBPC1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MYBPC1

Target: MYBPC1 (Myosin Binding Protein C, Slow Type (MYBPC1))

Alternative Name: MYBPC1

Background:

Synonyms: skeletal muscle slow isoform, slow-type, C protein, skeletal muscle slow isoform, C-protein, MYBPC1, MYBPCC, MYBPCS, Myosin binding protein C, slow type, Myosin-binding protein C, MYPC1_HUMAN, skeletal muscle C protein, Slow MyBP C, Slow MyBP-C.

Background: MYBPC1 is a 1,141 amino acid protein that contains three fibronectin type-III domains and seven Ig-like C2-type domains. Existing as a member of the immunoglobulin superfamily, MYBPC1 functions as a thick filament-associated protein that localizes to striated muscle bands in vertebrae and is thought to modify the activity of select ATPases. Additionally, MYBPC1 may play a role in the modulation of muscle contraction and in the overall structural integrity of the cell. The gene encoding MYBPC1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.