Olfactomedin 3 antibody (AA 101-200) (AbBy Fluor® 555)

Catalog No. ABIN1389035

The Rabbit Polyclonal anti-Olfactomedin 3 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect Olfactomedin 3 in samples from Mouse and Rat.

Quick Overview for Olfactomedin 3 antibody (AA 101-200) (AbBy Fluor® 555) (ABIN1389035)

Target: Olfactomedin 3 (OLFM3)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Olfactomedin 3 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Olfactomedin 3 Antibody (AbBy Fluor® 555)

Binding Specificity: AA 101-200

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OLFM3/Optimedin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Olfactomedin 3

Target: Olfactomedin 3 (OLFM3)

Alternative Name: OLFM3/Optimedin

Background:

Synonyms: Noe3, NOE3_HUMAN, Noelin 3, Noelin-3, NOELIN3, NOELIN3 V1, NOELIN3 V2, NOELIN3 V3, NOELIN3 V4, NOELIN3 V5, NOELIN3 V6, Olfactomedin 3, Olfactomedin related ER localized protein 3, Olfactomedin-3, Olfactomedin3, Olfm3, Optimedin.

Background: OLFM3 is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.