LALBA antibody (AA 61-142) (AbBy Fluor® 488)

Catalog No. ABIN1389454

This Rabbit Polyclonal antibody specifically detects LALBA in WB, IF (p) and IF (cc). It exhibits reactivity toward Human.

Quick Overview for LALBA antibody (AA 61-142) (AbBy Fluor® 488) (ABIN1389454)

Target: LALBA (Lactalbumin, alpha- (LALBA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LALBA antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-LALBA Antibody (AbBy Fluor® 488)

Binding Specificity: AA 61-142

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LALBA/alpha Lactalbumin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LALBA

Target: LALBA (Lactalbumin, alpha- (LALBA))

Alternative Name: LALBA/alpha Lactalbumin

Background:

Synonyms: a-LACTA, alfaLA, Alpha-lactalbumin, Lactalbumin alpha, Lactose synthase B protein, LALBA, LALBA_HUMAN, Lysozyme-like protein 7, LYZL7.

Background: Alpha-lactalbumin is the B protein of lactose synthetase secreted by the mammary epithelial cells. It is a potent Ca2+-elevating and apoptosis-inducing agent with broad, yet selective, cytotoxic activity. Multimeric ?lactalbumin has been shown to kill all transformed, embryonic and lymphoid cells tested, but not mature epithelial elements. This suggests that milk contributes to mucosal immunity not only by furnishing antimicrobial molecules but also by policing the function of lymphocytes and epithelium. ?lactalbumin may be helpful in discovering the site of origin of metastatic breast tumors. Human lactalbumin contains 123 amino acid residues. Comparison of the 5' flanking sequences of the two Alpha-lactalbumin genes with those of five casein genes reveals the presence of a highly conserved region extending from position -140 to -110 in all seven sequences examined, suggesting a possible regulatory role in the hormonal control or tissue-specific expression of milk protein genes in the mammary gland.

Gene ID: 3906

UniProt: P00709