Cadherin 4 antibody (AA 151-250) (AbBy Fluor® 488)

Catalog No. ABIN1389844

This Rabbit Polyclonal antibody specifically detects Cadherin 4 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for Cadherin 4 antibody (AA 151-250) (AbBy Fluor® 488) (ABIN1389844)

Target: Cadherin 4 (CDH4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 4 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Cadherin 4 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 151-250

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human R Cadherin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Cadherin 4

Target: Cadherin 4 (CDH4)

Alternative Name: R Cadherin

Background:

Synonyms: CADH4_HUMAN, Cadherin 4, Cadherin4, Cadherin-4, CDH 4, CDH-4, R CAD, R-CAD, R-cadherin, Retinal Cadherin.

Background: The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin b, to regulate cadherin function. R-cadherin (for retinal-cadherin, also designated cadherin-4), which was first identified in the retina of chicken, has been shown to be involved in the development of striated muscle and potentially epithelia in addition to its involvement in retinal development.

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size