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GRK4/GRK5/GRK6 (AA 181-280) antibody (AbBy Fluor® 555)

The Rabbit Polyclonal anti- antibody has been validated for IF (cc) and IF (p). It is suitable to detect in samples from Human.
Catalog No. ABIN1390073

Quick Overview for GRK4/GRK5/GRK6 (AA 181-280) antibody (AbBy Fluor® 555) (ABIN1390073)

Target

GRK4/GRK5/GRK6

Reactivity

  • 15
  • 1
  • 1
  • 1
Human

Host

  • 14
  • 1
Rabbit

Clonality

  • 14
  • 1
Polyclonal

Conjugate

  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
AbBy Fluor® 555

Application

  • 12
  • 12
  • 4
  • 3
  • 3
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

    • 14
    • 1
    AA 181-280

    Predicted Reactivity

    Human,Mouse,Rat,Dog,Cow,Pig,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human GRK6

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    GRK4/GRK5/GRK6

    Alternative Name

    GRK4, GRK5, GRK6

    Background

    Synonyms: GRK4: G protein-coupled receptor kinase 4, G protein-coupled receptor kinase GRK4, GPRK2L, GPRK4 GRK5: G protein-coupled receptor kinase 5, G protein-coupled receptor kinase GRK5, GPRK5 GRK6: G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6, GPRK6

    Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.

    Gene ID

    2868, 2869, 2870
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