HOXA6 antibody (AA 171-233) (AbBy Fluor® 647)

Catalog No. ABIN1390416

This anti-HOXA6 antibody is a Rabbit Polyclonal antibody detecting HOXA6 in WB, IF (cc) and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for HOXA6 antibody (AA 171-233) (AbBy Fluor® 647) (ABIN1390416)

Target: HOXA6 (Homeobox A6 (HOXA6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA6 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HOXA6 Antibody (AbBy Fluor® 647)

Binding Specificity: AA 171-233

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOXA6/HOX1B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HOXA6

Target: HOXA6 (Homeobox A6 (HOXA6))

Alternative Name: HOXA6/HOX1B

Background:

Synonyms: Homeo box 1B, Homeo box A6, Homeobox 1B, Homeobox A6, Homeobox protein Hox A6, Homeobox protein Hox-1B, Homeobox protein Hox-A6 antibody Homeobox protein HoxA6, HOX 1, Hox 1B, HOX1, HOX1.2, Hox1B, HOXA6, HX A6, HXA6, HXA6_HUMAN.

Background: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxA6 (homeobox A6), also known as HOX1B, is a 233 amino acid protein that localizes to the nucleus. Expressed during embryonic development, HoxA6 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA6 plays an important role in the regulation of gene expression, as well as morphogenesis and differentiation. The gene encoding HoxA6 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.