DLG3 antibody (AA 501-600) (FITC)

Catalog No. ABIN1390544

The Rabbit Polyclonal anti-DLG3 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect DLG3 in samples from Human and Rat.

Quick Overview for DLG3 antibody (AA 501-600) (FITC) (ABIN1390544)

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG3 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DLG3 Antibody (FITC)

Binding Specificity: AA 501-600

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAP102

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DLG3

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Alternative Name: SAP102/DLG3

Background:

Synonyms: Discs large homolog 3 neuroendocrine dlg, Discs large homolog 3, Disks large homolog 3, DLG 3, DLG3, DLG3_HUMAN, MPP3, MPP-3, KIAA1232, mKIAA1232, MRX 90, MRX, MRX90, NE Dlg, NEDLG, Neuroendocrine dlg, Neuroendocrine-DLG, OTTHUMP00000023475, OTTHUMP00000023476, OTTHUMP00000023477, SAP 102, SAP-102, SAP102, Synapse associated protein 102, Synapse-associated protein 102, XLMR, bA291O7.3, bA291O7.3.

Background: MPP3, also known as Discs large homolog 3 (DLG3), is a 585 amino acid protein belonging to the MAGUK family. Proteins in the MAGUK family, including CASK, ZO-1, ZO-2, p55 and MPP2, are known to regulate cell proliferation, intracellular junctions and signaling pathways by interacting with the cytoskeleton. MPP3 contains one guanylate kinase-like domain, one PDZ domain, two L27 domains and one SH3 domain. Via the PDZ domain, MMP3 interacts with the C-terminus of TSLC1. MMP3 has also been found to interact with SR-2A and SR-4.

Gene ID: 1741, 1739