RIMBP2 antibody (AA 951-1052) (AbBy Fluor® 488)

Catalog No. ABIN1390798

This Rabbit Polyclonal antibody specifically detects RIMBP2 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for RIMBP2 antibody (AA 951-1052) (AbBy Fluor® 488) (ABIN1390798)

Target: RIMBP2 (RIMS Binding Protein 2 (RIMBP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIMBP2 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-RIMBP2 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 951-1052

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RIMBP2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RIMBP2

Target: RIMBP2 (RIMS Binding Protein 2 (RIMBP2))

Alternative Name: RIMBP2

Background:

Synonyms: RIM-BP2, RIMB2_HUMAN, RIMBP2, RIMS-binding protein 2.

Background: RIMS-binding proteins (RIM-BPs) serve as adaptors during vesicle fusion and release by forming links between synaptic-vesicle fusion apparatuses and calcium channels. Specifically, RIM-BP2 (RIMS binding protein 2), also known as RBP2, is a 1,052 amino acid protein that links L-type Ca++ CP Alpha1D, N-type Ca++ CP Alpha1B, Rim1 and Rim2 during synaptic transmission. RIM-BP2 contains three fibronectin type-III domains and three SH3 domains, which are used to mediate binding to a proline-rich motifs. Existing as three alternatively spliced isoforms, RIM-BP2 is encoded by a gene that maps to human chromosome 12q24.33 and mouse chromosome 5 G1.3.

Gene ID: 23504