RSPH4A antibody (AA 435-482) (Biotin)

Catalog No. ABIN1391473

This Rabbit Polyclonal antibody specifically detects RSPH4A in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for RSPH4A antibody (AA 435-482) (Biotin) (ABIN1391473)

Target: RSPH4A (Radial Spoke Head 4 Homolog A (RSPH4A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSPH4A antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RSPH4A Antibody (Biotin)

Binding Specificity: AA 435-482

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RSPH4A/RSHL3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RSPH4A

Target: RSPH4A (Radial Spoke Head 4 Homolog A (RSPH4A))

Alternative Name: RSPH4A/RSHL3

Background:

Synonyms: CILD11, dJ412I7.1, Radial spoke head protein 4 homolog A, Radial spoke head-like protein 3, RSH4A_HUMAN, RSHL3, Rsph4a, RSPH6B, A230081C05.

Background: RSHL3 is predicted to be a component of the radial spoke head based on homology with proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. RSHL3 (radial spoke head-like protein 3), also known as radial spoke head protein 4 homolog A, is a 716 amino acid protein that belongs to the flagellar radial spoke RSP4/6 family. Mutations in the RSHL3 gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Existing as three alternatively spliced isoforms, the RSHL3 gene contains 6 exons, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly and P.falciparum, and maps to human chromosome 6q22.1.